Poboljšanje stabilnosti probiotskog proizvoda sa Lactiplantibacillus plantarum 299v uvođenjem laminatnih („flow pack“) kesica Stručni rad
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U svakodnevnoj upotrebi širom sveta sve su zastupljeniji probiotski proizvodi. Paraleno s tim, i u stručnoj javnosti raste interesovanje za istraživanja njihove proizvodnje i primene. Stabilnost probiotskog proizvoda se u farmaceutskoj proizvodnji obezbeđuje izborom probiotskog soja, formulacije i izborom pakovanja. Pakovanje je završna faza proizvodnje i presudni je faktor za stabilnost probiotika radi održanja vijabilnosti u toku roka upotrebe. U ovom radu opisan je izbor dodatnog pakovanja kapsuliranog probiotika Lactiplantibacillus plantarum 299v. Ispitivan je efekat dodatne zaštite blistera u laminatnim kesicama (engl. flow pack bag). Odabrani su blisteri napravljeni od PVC/PVdC/PE (polivinil hlorid/poliviniliden hlorid/polietilen) folije i aluminijumske folije, koji su zatim paraleno ispitani u poređenju sa blisterima pakovanim u dodatne kesice punjene inertnim gasom. Poređenjem vijabilnosti probiotskih ćelija laktobacila u uzorcima blistera u kesicama u odnosu na dva uzorka blistera bez tih kesica uočena je bolja zaštita probotskih ćelija od kiseonika, svetlosti i vlage u dodatnom pakovanju. Uvođenjem dodatne zaštite blistera u kesicama dobijena je za 11 % veća vijabilnost probiotika u poređenju sa uzorcima bez kesica posle 24 meseci što omogućava komformnije čuvanje proizvoda tokom upotrebe.
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