Zeta potential titration and Kelvin probe force microscopy as tools for the design of biomaterials Abstract

Glavni sadržaj članka

Silvia Spriano
Sara Ferraris
Francesca Gamna
Andrea Cochis
Lia Rimondini
https://orcid.org/0000-0002-7785-2282
Alessandro C. Scalia
Ajay Kumar
Biljana Mojsoska

Apstrakt

The biomaterials’ surface is the place where biomaterials, physiological fluids, proteins, and cells meet determining the host response. Surface features such as chemical composition, exposed functional groups, zeta and electric potential, wettability, topography, and roughness strongly affect this response. Surface functionalization and coating with biomolecules are strategic tools to modulate surface properties and control the biomaterial outcome. The design of a functionalization or coating process goes through the following main steps: selection of the biomolecule and process parameters, identification of the effective presence of the biomolecule on the surface and type of bond, and evaluation of the biological response. The role of advanced characterization techniques in these steps is here discussed.

Detalji članka

Rubrika

Antimicrobial biomaterials and strategies

Kako citirati

[1]
S. . Spriano, “Zeta potential titration and Kelvin probe force microscopy as tools for the design of biomaterials: Abstract”, Hem Ind, vol. 78, no. 1S, p. 56, Mar. 2024, Accessed: Dec. 22, 2024. [Online]. Available: https://www.ache-pub.org.rs/index.php/HemInd/article/view/1303

Reference

F. Gamna, A.M. Wiecek, A. Cochis, J. Barberi, A.C. Scalia, L. Rimondini, S. Spriano. Grafting of alpha-tocopheryl phosphate on chemically treated Ti-6Al-4V for antibacterial bone implants. Applied Surface Science 2023; 619: 156681, https://doi.org/10.1016/j.apsusc.2023.156681.

F. Gamna, A. Cochis, B. Mojsoska, A. Kumar, L. Rimondini, S. Spriano. functionalization with the synthetic peptoid GN2-Npm9 as a strategy for antibacterial and biocompatible titanium implants. Helyon 2024; 10: e24246, https://doi.org/10.1016/j.heliyon.2024.e24246

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