Physico-chemical and biological properties of dental calcium silicate cements - literature review

Main Article Content

Dragan V. Ilić
Đorđe M. Antonijević
Vladimir M. Biočanin
Božana Čolović
Vesna Danilović
Vladimir S. Komlev
Anastasia Y. Teterina
Vukoman R. Jokanović


Dental cement materials have been developed with the aim to replace hard dental tissues. The first material used for pulp capping, root canal obturation, bifurcation perforation and apexification is calcium hydroxide (in 1920). A half century later, glass-ionomer cements began to suppress it as dentine substitutes. Finally, in the 1990s, calcium silicate (CS) material appeared in the dental research community as the most promising dentine substitute capable to adequately meet all clinical requirements. The aim of this paper is to present an overview of literature related to studies about CS materials taking into account their physical, chemical and biological properties and clinical applications. This review aims to discuss beneficial and adverse characteristics of CSs concerning interactions to the hard dentine and soft pulp/periodontal tissues. This review article deals with the literature data about currently commercially available CS concerning laboratory and clinical findings. 109 scientific articles were analyzed of which 62 references reported in vitro and 26 in vivo investigations while 21 references comprised reports, reviews and books dealing with both, in vitro and in vivo investigations. Although further data collection is necessary, CSs are promising materials that represent a gold standard for numerous dental clinical procedures.

Article Details

Engineering of Materials - Biomaterials
Author Biographies

Dragan V. Ilić, Department for Conservative Dentistry, School of Dental Medicine, University of Belgrade, Serbia


Đorđe M. Antonijević, School of Dental Medicine, University of Belgrade, Belgrade, Serbia; Laboratory of Atomic Physics, Institute for Nuclear Sciences “Vinča”, University of Belgrade, Belgrade and Laboratory of Anthropology, School of Medicine, University of Belgrade, Belgrade,


Vladimir M. Biočanin, Faculty of Dentistry, University of Business Academy, Novi Sad

Associate prof PhD, Dpt. for oral Surgery

Božana Čolović, Laboratory for atomic physics, Institute for nuclear sciences “Vinca”, University of Belgrade, Serbia


Vladimir S. Komlev, A. A. Baikov Institute of Metallurgy and Materials Science (A.A. Baikov IMET RAS), Moscow

PhD vice director

Anastasia Y. Teterina, A. A. Baikov Institute of Metallurgy and Materials Science (A.A. Baikov IMET RAS), Moscow


Vukoman R. Jokanović, Laboratory of Atomic Physics, Institute for Nuclear Sciences “Vinča”, University of Belgrade, Belgrade and ALBOS d.o.o



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