Characterization of Vaccinium myrtillus leaf extract-loaded liposomes Abstract
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Abstract
Vaccinium myrtillus L. leaves contain bioactive components, such as polyphenols, stilbenes, iridoid glycosides, fatty acids, and fibers. However, polyphenols possess low solubility, stability, and bioavailability, thus the encapsulation of the mentioned active principles in different carriers is necessary. Liposomes are widely used as a carrier for the encapsulation, preservation, and controlled release of polyphenols in various products. Therefore, the aims of the presented research are the development and characterization of V. myrillus leaf extract-loaded liposomes via the determination of encapsulation efficiency, particle size, polydispersity index (PDI), zeta potential, and mobility.
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References
Ștefănescu, R., Laczkó-Zöld, E., Ősz, B.E., Vari, C.E. An Updated Systematic Review of Vaccinium myrtillus Leaves: Phytochemistry and Pharmacology. Pharmaceutics 2022; 15(1): 16. https://doi.org/10.3390/pharmaceutics15010016
Munin, A., Edwards-Lévy, F. Encapsulation of natural polyphenolic compounds; a review. Pharmaceutics 2011; 3: 793–829.
Jovanović, A.A., Ćujić, D., Stojadinović, B., Čutović, N., Živković, J., Šavikin, K. Liposomal Bilayer as a Carrier of Rosa canina L. Seed Oil: Physicochemical Characterization, Stability, and Biological Potential. Molecules 2022; 28: 276.
Jovanović, A., Balanč, B., Ota, A., Pegi, A., Djordjević, V., Šavikin, K., Bugarski, B., Nedović, V., Poklar-Ulrih, N. Comparative Effects of Cholesterol and β-Sitosterol on the Liposome Membrane Characteristics. Eur. J. Lipid Sci. Technol. 2018; 120: 1–41