Innovative hydroxyapatite-based coatings for bone implants: A multifaceted approach Abstract
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Abstract
Tissue engineering strives for innovative solutions in addressing challenges associated with contemporary bone tissue implants. This study focuses on the electrophoretic deposition (EPD) of hydroxyapatite-based bioceramic composites containing antibacterial agents onto titanium surfaces. Two composite coatings, hydroxyapatite/chitosan (HAP/CS) and hydroxyapatite/chitosan/gentamicin (HAP/CS/Gent) were developed to combat issues such as poor adhesion, limited antibacterial potential, limited bioactivity, and potential toxicity of implant materials.
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Funding data
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Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja
Grant numbers 451-03-47/2023–01/200287;451-03-47/2023–01/200023 -
Horizon 2020
Grant numbers 952033
References
Stevanović M., Đošić M., Janković A., Kojić V., Vukašinović-Sekulić M., Stojanović J., Odović J., Crevar Sakač M., Rhee K.Y., Mišković-Stanković V., Gentamicin-Loaded Bioactive Hydroxyapatite/Chitosan Composite Coating Electrodeposited on Titanium, ACS Biomaterials Science & Engineering (2018); 4 (12): 3994-4007, https://doi.org/10.1021/acsbiomaterials.8b00859