Bioengineering for creating biomimetic microenvironments: bioreactors and biomaterials Abstract

Main Article Content

Jasmina Stojkovska
https://orcid.org/0000-0002-6732-3037
Jovana Zvicer
https://orcid.org/0000-0002-5163-8368
Jelena Petrović
https://orcid.org/0000-0001-9161-4806
Ivana Banićević
https://orcid.org/0000-0003-1494-3264
Mia Milošević
https://orcid.org/0000-0003-3376-4317
Bojana Obradović
https://orcid.org/0000-0002-7276-0442

Abstract

Millions of patients are still awaiting new therapies as the traditional models rely on monolayer cell (2D) cultures and in vivo studies, which have numerous limitations resulting in misleading conclusions. Consequently, there is a burning need for the development of alternative 3D models able to accurately mimic the complexity of human diseases. This research aim is to create microenvironments based on biomimetic bioreactors and alginate hydrogels as cell carriers for reliable disease research and drug screening.

Article Details

Section

Cancer research

How to Cite

[1]
J. . Stojkovska, J. . Zvicer, J. . Petrović, I. . Banićević, M. . Milošević, and B. . Obradović, “Bioengineering for creating biomimetic microenvironments: bioreactors and biomaterials: Abstract”, Hem Ind, vol. 78, no. 1S, p. 18, Mar. 2024, Accessed: Dec. 22, 2024. [Online]. Available: https://www.ache-pub.org.rs/index.php/HemInd/article/view/1260

Funding data

References

Totti S, Allenby MC, Dos Santos SB, Mantalaris A, Velliou E. RSC Adv. 2018; 8: 20928-20940 https://doi.org/10.1039/C8RA02633E

Gupta P, Totti S, Pérez-Mancera PA, Dyke E, Nisbet A, Schettino G, Webb R, Velliou EG. RSC Adv. 2019; 9: 41649-41663 https://doi.org/10.1039/C9RA09123H

Gupta P, Pérez-Mancera PA, Kocher H, Nisbet A, Schettino G, Velliou EG. Front. Bioeng. Biotechnol. 2020; 8 (290). https://doi.org/10.3389/fbioe.2020.00290

Gupta P, Bermejo-Rodriguez C, Kocher H, Pérez-Mancera PA, Velliou EG. Adv. Biol. 2024; 2300580. https://doi.org/10.1002/adbi.202300580

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